BIOPEP-UWM: Report

ID 99
Name bitter peptide
sequence
RGPFPIIV
Function:
(Rcaf) 250
 
Number of residues
8
Activity code
bi
Activity :
bitter
Chemical mass 898.1000 Monoisotopic mass 897.5420
EC50 :
0.00 µM


Bibliographic data:
Authors
Tamura M., Miyoshi T., Mori N., Kinomura K., Kawaguchi M., Ishibashi N., Okai H.
Title
Mechanism of bitter casting potency of peptides using O-aminoacyl sugars as model compounds. Agric. Biol. Chem., 54, 1401-1409, 1990
Year Source
1990 Journal


Additional information:
BIOPEP database of sensory peptides and amino acids


SMILES: N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N1CCC[C@@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)O

InChI=1S/C44H71N11O9/c1-7-26(5)35(41(61)53-36(27(6)8-2)40(60)51-34(25(3)4)43(63)64)52-39(59)32-19-14-22-55(32)42(62)30(23-28-15-10-9-11-16-28)50-38(58)31-18-13-21-54(31)33(56)24-49-37(57)29(45)17-12-20-48-44(46)47/h9-11,15-16,25-27,29-32,34-36H,7-8,12-14,17-24,45H2,1-6H3,(H,49,57)(H,50,58)(H,51,60)(H,52,59)(H,53,61)(H,63,64)(H4,46,47,48)/t26-,27-,29-,30-,31+,32+,34-,35-,36-/m0/s1

InChIKey: CWVNDSADIDMCFJ-OGTKHFNDSA-N


Other references concerning peptide:

Minamiura N., Matsumura Y., Fukumoto J., Yamamaoto T., 1972, Bitter peptides in cow milk casein digesta with bacterial proteinase. Part 1. Isolation and determination of amino acid sequence of a bitter peptide. Agric. Biol. Chem., 36, 588-595

Lemieux L., Simard R. E., 1992, Bitter flavour in dairy products. II. A review of bitter peptides from caseins: their formation, isolation and identification, structure masking and inhibition. Lait, 72, 335-382


Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: XM02-001) according to the AHTPDB database; the BIOPEP database of bioactive peptides


Database reference:
AHTPDB: ID 6755

BIOPEP database of bioactive peptides: ID 8160

SATPdb: ID satpdb28607