BIOPEP-UWM: Report

ID 11
Name DPPIV inhibitor
sequence
AGLPTEEKPPLL
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 1PFQ)
 
Number of residues
12
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 1264.4632 Monoisotopic mass 1263.7051
EC50 :
0.00 µM


Bibliographic data:
Authors
Garzón A. G., Veras F. F., Brandelli A., Drago S. R.
Title
Purification, identification and in silico studies of antioxidant, antidiabetogenic and antibacterial peptides obtained from sorghum spent grain hydrolysate. LWT, 153, 112414, 2022
Year Source
2022 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCCCN)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C58H97N13O18/c1-30(2)26-38(51(81)67-40(58(88)89)28-32(5)6)66-52(82)41-15-12-24-70(41)57(87)43-17-13-25-71(43)55(85)37(14-9-10-22-59)65-50(80)35(18-20-45(74)75)63-49(79)36(19-21-46(76)77)64-54(84)47(34(8)72)68-53(83)42-16-11-23-69(42)56(86)39(27-31(3)4)62-44(73)29-61-48(78)33(7)60/h30-43,47,72H,9-29,59-60H2,1-8H3,(H,61,78)(H,62,73)(H,63,79)(H,64,84)(H,65,80)(H,66,82)(H,67,81)(H,68,83)(H,74,75)(H,76,77)(H,88,89)/t33-,34+,35-,36-,37-,38-,39-,40-,41-,42-,43-,47-/m0/s1

InChIKey=HMSBGSZBCNOYLC-MOPQNTLFSA-N


Bioactivity predicted using molecular docking


Database reference: