BIOPEP-UWM: Report

ID 135
Name Bitterness suppressing peptide
sequence
NDPQF
Function:
Predicted ligand of bitternes receptor T2R14 (BitterDB ID: 14)
 
Number of residues
5
Activity code
bis
Activity :
bitterness suppressing
Chemical mass 619.6221 Monoisotopic mass 619.2593
EC50 :
0.00 µM


Bibliographic data:
Authors
Yu Z., Wang Y., Zhao W., Li J., Shuian D., Liu J.
Title
Identification of Oncorhynchus mykiss nebulin-derived peptides as bitter taste receptor TAS2R14 blockers by in silico screening and molecular docking. Food Chem., 368, 130839, 2022
Year Source
2022 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C27H37N7O10/c28-15(12-21(30)36)23(39)32-17(13-22(37)38)26(42)34-10-4-7-19(34)25(41)31-16(8-9-20(29)35)24(40)33-18(27(43)44)11-14-5-2-1-3-6-14/h1-3,5-6,15-19H,4,7-13,28H2,(H2,29,35)(H2,30,36)(H,31,41)(H,32,39)(H,33,40)(H,37,38)(H,43,44)/t15-,16-,17-,18-,19-/m0/s1

InChIKey=LZKLPRLOQMYZAX-VMXHOPILSA-N


Bioactivity predicted using molecular docking


Database reference: