BIOPEP-UWM: Report

ID 138
Name Bitterness suppressing peptide
sequence
DM
Function:
Predicted ligand of bitternes receptor T2R14 (BitterDB ID: 14)
 
Number of residues
2
Activity code
bis
Activity :
bitterness suppressing
Chemical mass 264.2992 Monoisotopic mass 264.0776
EC50 :
0.00 µM


Bibliographic data:
Authors
Yu Z., Wang Y., Zhao W., Li J., Shuian D., Liu J.
Title
Identification of Oncorhynchus mykiss nebulin-derived peptides as bitter taste receptor TAS2R14 blockers by in silico screening and molecular docking. Food Chem., 368, 130839, 2022
Year Source
2022 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C9H16N2O5S/c1-17-3-2-6(9(15)16)11-8(14)5(10)4-7(12)13/h5-6H,2-4,10H2,1H3,(H,11,14)(H,12,13)(H,15,16)/t5-,6-/m0/s1

InChIKey: DYDKXJWQCIVTMR-WDSKDSINSA-N


Bioactivity predicted using molecular docking


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9075); the PubChem database


Database reference:
AHTPDB: ID 1398, 4713, 5142, 6167

BioPepDB: ID biopep00145

BIOPEP-UWM database of bioactive peptides: ID 9075

ChemSpider: ID 8032284

SATPdb: ID satpdb11083