BIOPEP-UWM: Report

ID 140
Name Bitterness suppressing peptide
sequence
SM
Function:
Predicted ligand of bitternes receptor T2R14 (BitterDB ID: 14)
 
Number of residues
2
Activity code
bis
Activity :
bitterness suppressing
Chemical mass 236.2891 Monoisotopic mass 236.0827
EC50 :
0.00 µM


Bibliographic data:
Authors
Yu Z., Wang Y., Zhao W., Li J., Shuian D., Liu J.
Title
Identification of Oncorhynchus mykiss nebulin-derived peptides as bitter taste receptor TAS2R14 blockers by in silico screening and molecular docking. Food Chem., 368, 130839, 2022
Year Source
2022 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C8H16N2O4S/c1-15-3-2-6(8(13)14)10-7(12)5(9)4-11/h5-6,11H,2-4,9H2,1H3,(H,10,12)(H,13,14)/t5-,6-/m0/s1

InChIKey=PBUXMVYWOSKHMF-WDSKDSINSA-N


Bioactivity predicted using molecular docking


Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9507)


Database reference:
ACToR: ID 3227-09-6
BIOPEP-UWM database of bioactive peptides: ID 9507

ChEBI: ID 74817

ChemIDplus: ID 3227-09-6

ChemSpider: ID 133169

CTD: ID 3227-09-6

eChemPortal: ID 3227-09-6

EPA CompTox: ID DTXSID80186018

EPA DSSTox: ID DTXCID90108509

HMDB: ID HMDB29045

J-GLOBAL: ID 200907071691366701

Nikkaji: ID J151.284F

PubChem: CID 151087

SDBS: ID SDBS-9536

ZINC: ID ZINC000002575490