BIOPEP-UWM: Report

ID 150
Name ACE inhibitor
sequence
FPVGRGL

Function:
Predicted inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) (PDB ID: 1O86)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 744.8791 Monoisotopic mass 744.4270
EC50 :
0.00 µM



Bibliographic data:
Authors
Wenhui T., Shumin H., Yongliang Z., Liping S., Hua Y.
Title
Identification of in vitro angiotensin-converting enzyme and dipeptidyl peptidase IV inhibitory peptides from draft beer by virtual screening and molecular docking. J. Sci. Food Agric., 102, 1085-1094, 2022
Year Source
2022 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C35H56N10O8/c1-20(2)16-25(34(52)53)43-28(47)18-40-30(48)24(12-8-14-39-35(37)38)42-27(46)19-41-32(50)29(21(3)4)44-31(49)26-13-9-15-45(26)33(51)23(36)17-22-10-6-5-7-11-22/h5-7,10-11,20-21,23-26,29H,8-9,12-19,36H2,1-4H3,(H,40,48)(H,41,50)(H,42,46)(H,43,47)(H,44,49)(H,52,53)(H4,37,38,39)/t23-,24-,25-,26-,29-/m0/s1

InChIKey=PDQYQZYTPKBDKM-YIHYGEMESA-N


Bioactivity predicted by molecular docking


Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 5I7U) according to the BIOPEP-UWM Virtual database



Database reference:
BIOPEP-UWM Virtual database: ID