BIOPEP-UWM: Report

ID 212
Name Antithrombotic peptide
sequence
RNAVPITPTLNR

Function:
Predicted ligand of Thrombin (EC 3.4.21.5) (MEROPS ID: S01.217) (PDB code: 2BVR)
 
Number of residues
12
Activity code
at
Activity :
antithrombotic
Chemical mass 1351.5502 Monoisotopic mass 1350.7709
EC50 :
0.00 µM



Bibliographic data:
Authors
Tu M., Feng L., Wang Z., Qiao M., Shahidi F., Lu W., Du M.
Title
Sequence analysis and molecular docking of antithrombotic peptides from casein hydrolysate by trypsin digestion. J. Funct. Foods, 32, 313–323, 2017
Year Source
2017 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C77H130N24O25/c1-12-37(8)57(70(120)98-59(40(11)103)74(124)101-29-17-22-50(101)69(119)97-58(39(10)102)71(121)93-44(30-34(2)3)64(114)92-46(32-52(80)105)65(115)89-43(75(125)126)19-14-26-86-77(83)84)96-68(118)49-21-16-28-100(49)72(122)55(35(4)5)94-60(110)38(9)87-63(113)45(31-51(79)104)91-62(112)42(18-13-25-85-76(81)82)88-67(117)48-20-15-27-99(48)73(123)56(36(6)7)95-66(116)47(33-54(108)109)90-61(111)41(78)23-24-53(106)107/h34-50,55-59,102-103H,12-33,78H2,1-11H3,(H2,79,104)(H2,80,105)(H,87,113)(H,88,117)(H,89,115)(H,90,111)(H,91,112)(H,92,114)(H,93,121)(H,94,110)(H,95,116)(H,96,118)(H,97,119)(H,98,120)(H,106,107)(H,108,109)(H,125,126)(H4,81,82,85)(H4,83,84,86)/t37-,38-,39+,40+,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,55-,56-,57-,58-,59-/m0/s1

InChIKey=KCHCIAUQBPMKKQ-GEBAWBRLSA-N

Bioactivity predicted using molecular docking




Database reference:
DFBP: DFBPANTH0155