BIOPEP-UWM: Report

ID 248
Name Predicted antioxidative peptide
sequence
NDGPSR

Function:
Peptide predicted to bind ABTS•+ (PubChem CID 5360881); predicted ligand of murine Keap1 (PDB ID: 5CGJ), human MPO (EC 1.11.2.2; PDB ID: 5CGJ) and bovine xanthine oxidase (EC 1.17.3.2; PDB ID: 3NVY)
 
Number of residues
6
Activity code
ao
Activity :
antioxidative
Chemical mass 644.6332 Monoisotopic mass 644.2869
EC50 :
0.00 µM



Bibliographic data:
Authors
Ong J.-H., Koh J.-A., Cao H., Tan S.-A., Manan F. A., Wong F.-C., Chai T.-T.
Title
Purification, identification and characterization of antioxidant peptides from corn silk tryptic hydrolysate: an integrated in vitro-in silico approach. Antioxidants, 10, 1822, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(=O)O)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C24H40N10O11/c25-11(7-16(26)36)19(40)32-13(8-18(38)39)20(41)30-9-17(37)34-6-2-4-15(34)22(43)33-14(10-35)21(42)31-12(23(44)45)3-1-5-29-24(27)28/h11-15,35H,1-10,25H2,(H2,26,36)(H,30,41)(H,31,42)(H,32,40)(H,33,43)(H,38,39)(H,44,45)(H4,27,28,29)/t11-,12-,13-,14-,15-/m0/s1

InChIKey=CZOFIJPISUFRLT-YTFOTSKYSA-N


Preliminary predictions were done using QSAR (program AnOxPePred). Interactions between peptide and receptors were predicted using molecular docking.





Database reference: