BIOPEP-UWM: Report

ID 250
Name Predicted antioxidative peptide
sequence
NLEGYR

Function:
Predicted ligand of murine Keap1 (PDB ID: 5CGJ) and human MPO (EC 1.11.2.2; PDB ID: 5CGJ)
 
Number of residues
6
Activity code
ao
Activity :
antioxidative
Chemical mass 750.7978 Monoisotopic mass 750.3649
EC50 :
0.00 µM



Bibliographic data:
Authors
Ong J.-H., Koh J.-A., Cao H., Tan S.-A., Manan F. A., Wong F.-C., Chai T.-T.
Title
Purification, identification and characterization of antioxidant peptides from corn silk tryptic hydrolysate: an integrated in vitro-in silico approach. Antioxidants, 10, 1822, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C32H50N10O11/c1-16(2)12-22(42-27(48)19(33)14-24(34)44)29(50)40-20(9-10-26(46)47)28(49)38-15-25(45)39-23(13-17-5-7-18(43)8-6-17)30(51)41-21(31(52)53)4-3-11-37-32(35)36/h5-8,16,19-23,43H,3-4,9-15,33H2,1-2H3,(H2,34,44)(H,38,49)(H,39,45)(H,40,50)(H,41,51)(H,42,48)(H,46,47)(H,52,53)(H4,35,36,37)/t19-,20-,21-,22-,23-/m0/s1

InChIKey= XQJSWUKPXODVFE-VUBDRERZSA-N

Preliminary predictions were done using QSAR (program AnOxPePred). Interactions between peptide and receptors were predicted using molecular docking.



Database reference: