BIOPEP-UWM: Report

ID 281
Name XIAP inhibitor
sequence
QIGLF
Function:
Predicted ligand of ubiquitin ligase (XIAP) (EC 2.3.2.27) (Alpha Fold ID AF-P98170-F1-model-v2)
 
Number of residues
5
Activity code
xiap
Activity :
XIAP inhibitor
Chemical mass 576.6832 Monoisotopic mass 576.3261
EC50 :
0.00 µM


Bibliographic data:
Authors
Fatoki T. H., Aluko R. E., Udenigwe C. C.
Title
In silico investigation of molecular targets, pharmacokinetics, and biological activities of chicken egg ovalbumin protein hydrolysates. J. Food Bioact., 17, 34–48, 2022
Year Source
2022 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C28H44N6O7/c1-5-17(4)24(34-25(37)19(29)11-12-22(30)35)27(39)31-15-23(36)32-20(13-16(2)3)26(38)33-21(28(40)41)14-18-9-7-6-8-10-18/h6-10,16-17,19-21,24H,5,11-15,29H2,1-4H3,(H2,30,35)(H,31,39)(H,32,36)(H,33,38)(H,34,37)(H,40,41)/t17-,19-,20-,21-,24-/m0/s1

InChIKey=MTSHVTAATUWGIO-ZKEZPVKKSA-N


Bioactivity predicted using molecular docking


Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPD database, the BIOPEP-UWM database of bioactive peptides (ID 8395), the PubChem database
Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 9411)


Database reference:
AHTPDB: ID 4472, 4484

BioPepDB: ID biopep01142

BIOPEP-UWM database of bioactive peptides: ID 8395; 9411

J-GLOBAL: ID 201107097538228100

Nikkaji: ID J2.922.612A

PubChem: CID 101777178

SATPdb: ID satpdb24604