BIOPEP-UWM: Report

ID 311
Name ACE inhibitor
sequence
LVYPFPGPIPN

Function:
Predicted inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) (PDB ID: 1O8A)
 
Number of residues
11
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1213.4199 Monoisotopic mass 1212.6522
EC50 :
0.00 µM



Bibliographic data:
Authors
Wang Z., Zhang M., Zhao C., Li J., Wang J., Ma C., Ma D.
Title
ACE-inhibitory peptides in sodium-reduced cheese with probiotic: Identification, in silico prediction and molecular interaction. LWT, 200, 116198, 2024
Year Source
2024 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=O)N)C(=O)O

InChI=1S/C61H88N12O14/c1-7-36(6)51(60(85)73-28-14-20-47(73)55(80)67-43(61(86)87)32-48(63)75)69-56(81)45-18-11-25-70(45)49(76)33-64-53(78)44-17-12-26-71(44)58(83)41(30-37-15-9-8-10-16-37)65-54(79)46-19-13-27-72(46)59(84)42(31-38-21-23-39(74)24-22-38)66-57(82)50(35(4)5)68-52(77)40(62)29-34(2)3/h8-10,15-16,21-24,34-36,40-47,50-51,74H,7,11-14,17-20,25-33,62H2,1-6H3,(H2,63,75)(H,64,78)(H,65,79)(H,66,82)(H,67,80)(H,68,77)(H,69,81)(H,86,87)/t36-,40-,41-,42-,43-,44-,45-,46-,47-,50-,51-/m0/s1

InChIKey=WVNDETRGHVJDMG-JEXSQASBSA-N


Bioactivity predicted by molecular docking



Database reference: