BIOPEP-UWM: Report

ID 343
Name Predicted osteoanabolic peptide
sequence
VPQLE
Function:
Predicted ligand of Epidermal growth factor receptor (EGFR) (PDB ID: 1IV0)
 
Number of residues
5
Activity code
ost
Activity :
osteoanabolic
Chemical mass 584.6606 Monoisotopic mass 584.3159
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhang Y., Niu Y., Fu C., Zhu L., Wang H., Yi Y., Xu W., Guo D.
Title
Preparation, identification and screening of anti-osteoporosis milk-derived peptides: Intervention effects in osteoporosis rats. Food Biosci., 62, 105120, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database

SMILES: N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)O

InChI=1S/C59H101N17O22/c1-7-27(3)44(55(93)71-37(59(97)98)25-41(65)81)72-57(95)47(30(6)78)75-54(92)38-16-13-23-76(38)58(96)45(28(4)8-2)73-51(89)34(18-20-42(82)83)68-56(94)46(29(5)77)74-50(88)32(15-10-12-22-61)66-53(91)36(26-43(84)85)70-49(87)33(17-19-39(63)79)67-52(90)35(24-40(64)80)69-48(86)31(62)14-9-11-21-60/h27-38,44-47,77-78H,7-26,60-62H2,1-6H3,(H2,63,79)(H2,64,80)(H2,65,81)(H,66,91)(H,67,90)(H,68,94)(H,69,86)(H,70,87)(H,71,93)(H,72,95)(H,73,89)(H,74,88)(H,75,92)(H,82,83)(H,84,85)(H,97,98)/t27-,28-,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,44-,45-,46-,47-/m0/s1

InChIKey=NWPXUQSCEAEMTL-PJEQLMJHSA-N


Bioactivity predicted using molecular docking


Database reference: