BIOPEP-UWM: Report

ID 345
Name Predicted osteoanabolic peptide
sequence
IPAVF

Function:
Predicted ligand of Epidermal growth factor receptor (EGFR) (PDB ID: 1IV0)
 
Number of residues
5
Activity code
ost
Activity :
osteoanabolic
Chemical mass 545.6692 Monoisotopic mass 545.3203
EC50 :
0.00 µM



Bibliographic data:
Authors
Zhang Y., Niu Y., Fu C., Zhu L., Wang H., Yi Y., Xu W., Guo D.
Title
Preparation, identification and screening of anti-osteoporosis milk-derived peptides: Intervention effects in osteoporosis rats. Food Biosci., 62, 105120, 2024
Year Source
2024 Journal



Additional information:
BIOPEP-UWM Virtual database

SMILES: N[C@@H]([C@H](CC)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O

InChI=1S/C28H43N5O6/c1-6-17(4)22(29)27(37)33-14-10-13-21(33)25(35)30-18(5)24(34)32-23(16(2)3)26(36)31-20(28(38)39)15-19-11-8-7-9-12-19/h7-9,11-12,16-18,20-23H,6,10,13-15,29H2,1-5H3,(H,30,35)(H,31,36)(H,32,34)(H,38,39)/t17-,18-,20-,21-,22-,23-/m0/s1

InChIKey=RDMIXXDHHVQQKJ-PPSMKJHDSA-N


Bioactivity predicted using molecular docking


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 10672)
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8620); the DFBP database
Antiviral peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10670)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 502); the EROP-Moscow database




Database reference: