BIOPEP-UWM: Report

ID 356
Name Pancreatic lipase inhibitor
sequence
NHTW
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
4
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 556.5697 Monoisotopic mass 556.2387
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(=O)N)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C25H32N8O7/c1-12(34)21(24(38)32-19(25(39)40)6-13-9-29-17-5-3-2-4-15(13)17)33-23(37)18(7-14-10-28-11-30-14)31-22(36)16(26)8-20(27)35/h2-5,9-12,16,18-19,21,29,34H,6-8,26H2,1H3,(H2,27,35)(H,28,30)(H,31,36)(H,32,38)(H,33,37)(H,39,40)/t12-,16+,18+,19+,21+/m1/s1

InChIKey=UIWDDJAKLWQJHM-PCKPCOSRSA-N


Activity predicted using molecular docking.


Database reference: