BIOPEP-UWM: Report

ID 359
Name Pancreatic lipase inhibitor
sequence
HDHLLF
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
6
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 780.8683 Monoisotopic mass 780.3907
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C37H52N10O9/c1-20(2)10-26(33(51)44-27(11-21(3)4)34(52)47-30(37(55)56)12-22-8-6-5-7-9-22)45-35(53)28(14-24-17-40-19-42-24)46-36(54)29(15-31(48)49)43-32(50)25(38)13-23-16-39-18-41-23/h5-9,16-21,25-30H,10-15,38H2,1-4H3,(H,39,41)(H,40,42)(H,43,50)(H,44,51)(H,45,53)(H,46,54)(H,47,52)(H,48,49)(H,55,56)/t25-,26-,27-,28-,29-,30-/m0/s1

InChIKey=LCFDDDWHYVDDHI-WPMUBMLPSA-N


Activity predicted using molecular docking.


Database reference: