BIOPEP-UWM: Report

ID 361
Name Pancreatic lipase inhibitor
sequence
PAAY
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
4
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 420.4584 Monoisotopic mass 420.2002
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C20H28N4O6/c1-11(23-19(28)15-4-3-9-21-15)17(26)22-12(2)18(27)24-16(20(29)30)10-13-5-7-14(25)8-6-13/h5-8,11-12,15-16,21,25H,3-4,9-10H2,1-2H3,(H,22,26)(H,23,28)(H,24,27)(H,29,30)/t11-,12-,15-,16-/m0/s1

InChIKey=GWAAGDFTWLSNRV-APYUEPQZSA-N


Activity predicted using molecular docking.


Database reference: