BIOPEP-UWM: Report

ID 363
Name Pancreatic lipase inhibitor
sequence
MPAAASR
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
7
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 702.8223 Monoisotopic mass 702.3472
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCSC)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C28H50N10O9S/c1-14(33-22(41)15(2)35-25(44)20-8-6-11-38(20)26(45)17(29)9-12-48-4)21(40)34-16(3)23(42)37-19(13-39)24(43)36-18(27(46)47)7-5-10-32-28(30)31/h14-20,39H,5-13,29H2,1-4H3,(H,33,41)(H,34,40)(H,35,44)(H,36,43)(H,37,42)(H,46,47)(H4,30,31,32)/t14-,15-,16-,17-,18-,19-,20-/m0/s1

InChIKey=BDTPBSQYQMGDTH-RBZZARIASA-N


Activity predicted using molecular docking.

InChI=1S/C22H30N4O6/c1-13(22(31)32)24-19(28)17-4-2-10-25(17)21(30)18-5-3-11-26(18)20(29)16(23)12-14-6-8-15(27)9-7-14/h6-9,13,16-18,27H,2-5,10-12,23H2,1H3,(H,24,28)(H,31,32)/t13-,16-,17-,18-/m0/s1

InChIKey=AYUINYNZOPAJQB-MGHWNKPDSA-N


Activity predicted using molecular docking.


Database reference: