BIOPEP-UWM: Report

ID 364
Name Pancreatic lipase inhibitor
sequence
RAPRW
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
5
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 684.7877 Monoisotopic mass 684.3810
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C31H48N12O6/c1-17(40-25(44)20(32)8-4-12-37-30(33)34)28(47)43-14-6-11-24(43)27(46)41-22(10-5-13-38-31(35)36)26(45)42-23(29(48)49)15-18-16-39-21-9-3-2-7-19(18)21/h2-3,7,9,16-17,20,22-24,39H,4-6,8,10-15,32H2,1H3,(H,40,44)(H,41,46)(H,42,45)(H,48,49)(H4,33,34,37)(H4,35,36,38)/t17-,20-,22-,23-,24-/m0/s1

InChIKey=GHUWXQRWJWUEAU-UDZUZDSLSA-N


Activity predicted using molecular docking.


Database reference: