BIOPEP-UWM: Report

ID 365
Name Pancreatic lipase inhibitor
sequence
FDVVPK
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
6
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 703.8240 Monoisotopic mass 703.3892
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C34H53N7O9/c1-19(2)27(39-30(45)24(18-26(42)43)38-29(44)22(36)17-21-11-6-5-7-12-21)32(47)40-28(20(3)4)33(48)41-16-10-14-25(41)31(46)37-23(34(49)50)13-8-9-15-35/h5-7,11-12,19-20,22-25,27-28H,8-10,13-18,35-36H2,1-4H3,(H,37,46)(H,38,44)(H,39,45)(H,40,47)(H,42,43)(H,49,50)/t22-,23-,24-,25-,27-,28-/m0/s1

InChIKey=SWXQVBDXRPQPLR-FEZCWRLCSA-N


Activity predicted using molecular docking.


Database reference: