BIOPEP-UWM: Report

ID 380
Name Pancreatic lipase inhibitor
sequence
APLY
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
4
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 462.5379 Monoisotopic mass 462.2470
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C23H34N4O6/c1-13(2)11-17(25-21(30)19-5-4-10-27(19)22(31)14(3)24)20(29)26-18(23(32)33)12-15-6-8-16(28)9-7-15/h6-9,13-14,17-19,28H,4-5,10-12,24H2,1-3H3,(H,25,30)(H,26,29)(H,32,33)/t14-,17-,18-,19-/m0/s1

InChIKey=DLHRNUAODHRKSG-QZHFEQFPSA-N


Activity predicted using molecular docking.


Database reference: