BIOPEP-UWM: Report

ID 383
Name Pancreatic lipase inhibitor
sequence
RPPPPVAM
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
8
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 864.0652 Monoisotopic mass 863.4673
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C39H65N11O9S/c1-22(2)30(33(53)44-23(3)31(51)45-25(38(58)59)15-21-60-4)46-32(52)26-11-6-17-47(26)35(55)28-13-8-19-49(28)37(57)29-14-9-20-50(29)36(56)27-12-7-18-48(27)34(54)24(40)10-5-16-43-39(41)42/h22-30H,5-21,40H2,1-4H3,(H,44,53)(H,45,51)(H,46,52)(H,58,59)(H4,41,42,43)/t23-,24-,25-,26-,27-,28-,29-,30-/m0/s1

InChIKey=FSAUDWGHZZGAED-JEDGRRCBSA-N


Activity predicted using molecular docking.


Database reference: