BIOPEP-UWM: Report

ID 385
Name Pancreatic lipase inhibitor
sequence
QMCNPVPK
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
8
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 916.1194 Monoisotopic mass 915.4292
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C38H65N11O11S2/c1-20(2)30(37(58)49-16-7-9-26(49)34(55)44-23(38(59)60)8-4-5-14-39)47-35(56)27-10-6-15-48(27)36(57)24(18-29(42)51)45-33(54)25(19-61)46-32(53)22(13-17-62-3)43-31(52)21(40)11-12-28(41)50/h20-27,30,61H,4-19,39-40H2,1-3H3,(H2,41,50)(H2,42,51)(H,43,52)(H,44,55)(H,45,54)(H,46,53)(H,47,56)(H,59,60)/t21-,22-,23-,24-,25-,26-,27-,30-/m0/s1

InChIKey=PPAQSIIVEOABPC-IIBWBHLISA-N


Activity predicted using molecular docking.


Database reference: