BIOPEP-UWM: Report

ID 387
Name Pancreatic lipase inhibitor
sequence
FDELLF
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
6
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 782.8775 Monoisotopic mass 782.3837
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C39H54N6O11/c1-22(2)17-28(36(52)44-29(18-23(3)4)37(53)45-31(39(55)56)20-25-13-9-6-10-14-25)43-35(51)27(15-16-32(46)47)41-38(54)30(21-33(48)49)42-34(50)26(40)19-24-11-7-5-8-12-24/h5-14,22-23,26-31H,15-21,40H2,1-4H3,(H,41,54)(H,42,50)(H,43,51)(H,44,52)(H,45,53)(H,46,47)(H,48,49)(H,55,56)/t26-,27-,28-,29-,30-,31-/m0/s1

InChIKey=KNLHHSCRRYXXHF-HPMAGDRPSA-N


Activity predicted using molecular docking.


Database reference: