BIOPEP-UWM: Report

ID 388
Name Pancreatic lipase inhibitor
sequence
LYQEPVLGPVRGPFPILV
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
18
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 1994.3723 Monoisotopic mass 1993.1365
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)O

InChI=1S/C97H152N22O23/c1-15-57(14)80(93(138)110-66(46-53(6)7)86(131)114-79(56(12)13)96(141)142)115-90(135)72-30-23-43-119(72)95(140)68(48-58-24-17-16-18-25-58)111-87(132)69-27-20-40-116(69)74(122)49-103-82(127)62(26-19-39-102-97(100)101)106-91(136)77(54(8)9)112-88(133)70-28-21-41-117(70)75(123)50-104-83(128)65(45-52(4)5)109-92(137)78(55(10)11)113-89(134)71-29-22-42-118(71)94(139)64(36-38-76(124)125)107-84(129)63(35-37-73(99)121)105-85(130)67(47-59-31-33-60(120)34-32-59)108-81(126)61(98)44-51(2)3/h16-18,24-25,31-34,51-57,61-72,77-80,120H,15,19-23,26-30,35-50,98H2,1-14H3,(H2,99,121)(H,103,127)(H,104,128)(H,105,130)(H,106,136)(H,107,129)(H,108,126)(H,109,137)(H,110,138)(H,111,132)(H,112,133)(H,113,134)(H,114,131)(H,115,135)(H,124,125)(H,141,142)(H4,100,101,102)/t57-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,77-,78-,79-,80-/m0/s1

InChIKey=UUZUZNCLKOOTMX-KYGQNWDVSA-N


Activity predicted using molecular docking.


Database reference: