BIOPEP-UWM: Report

ID 389
Name Pancreatic lipase inhibitor
sequence
IHPFAQAQS
Function:
Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH)
 
Number of residues
9
Activity code
plip
Activity :
pancreatic lipase inhibitor
Chemical mass 998.0901 Monoisotopic mass 997.4966
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Ajayi F. F., Alyafei A. S., Yap P.-G., Gan C.-Y., Maqsood S.
Title
Unlocking the hypolipidemic potential of bioactive peptides derived from probiotic fermented cattle, camel, goat, and sheep milk: a comprehensive investigation through in vitro, in silico, and molecular docking studies. Front. Sustain. Food Syst., 8, 1443708, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CO)C(=O)O

InChI=1S/C45H67N13O13/c1-5-23(2)36(48)43(68)56-31(19-27-20-49-22-50-27)44(69)58-17-9-12-33(58)42(67)55-30(18-26-10-7-6-8-11-26)41(66)52-25(4)38(63)53-28(13-15-34(46)60)39(64)51-24(3)37(62)54-29(14-16-35(47)61)40(65)57-32(21-59)45(70)71/h6-8,10-11,20,22-25,28-33,36,59H,5,9,12-19,21,48H2,1-4H3,(H2,46,60)(H2,47,61)(H,49,50)(H,51,64)(H,52,66)(H,53,63)(H,54,62)(H,55,67)(H,56,68)(H,57,65)(H,70,71)/t23-,24-,25-,28-,29-,30-,31-,32-,33-,36-/m0/s1

InChIKey=MHUHUGUPFMOOIK-VEQLQRLESA-N


Activity predicted using molecular docking.


Database reference: