BIOPEP-UWM: Report

ID 413
Name Dipeptidyl peptidase IV inhibitor
sequence
QKDFSH
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
6
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 760.7927 Monoisotopic mass 760.3493
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CO)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)O

InChI=1S/C33H48N10O11/c34-11-5-4-8-21(39-28(48)20(35)9-10-26(36)45)29(49)41-23(14-27(46)47)31(51)40-22(12-18-6-2-1-3-7-18)30(50)43-25(16-44)32(52)42-24(33(53)54)13-19-15-37-17-38-19/h1-3,6-7,15,17,20-25,44H,4-5,8-14,16,34-35H2,(H2,36,45)(H,37,38)(H,39,48)(H,40,51)(H,41,49)(H,42,52)(H,43,50)(H,46,47)(H,53,54)/t20-,21-,22-,23-,24-,25-/m0/s1

InChIKey=KNOUGBQGUZXOCL-OOPVGHQCSA-N


Bioactivity predicted by molecular docking


Database reference: