BIOPEP-UWM: Report

ID 420
Name Dipeptidyl peptidase IV inhibitor
sequence
WRPLN
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
5
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 684.7844 Monoisotopic mass 684.3697
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)O

InChI=1S/C32H48N10O7/c1-17(2)13-23(28(45)41-24(31(48)49)15-26(34)43)40-29(46)25-10-6-12-42(25)30(47)22(9-5-11-37-32(35)36)39-27(44)20(33)14-18-16-38-21-8-4-3-7-19(18)21/h3-4,7-8,16-17,20,22-25,38H,5-6,9-15,33H2,1-2H3,(H2,34,43)(H,39,44)(H,40,46)(H,41,45)(H,48,49)(H4,35,36,37)/t20-,22-,23-,24-,25-/m0/s1

InChIKey=NCJUGDFVMQRHNB-NPJMLQJUSA-N


Bioactivity predicted by molecular docking


Database reference: