BIOPEP-UWM: Report

ID 426
Name Dipeptidyl peptidase IV inhibitor
sequence
CCVMLNPLW
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
9
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 1078.3715 Monoisotopic mass 1077.4793
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CS)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C48H75N11O11S3/c1-24(2)17-32(53-41(62)31(14-16-73-7)52-46(67)39(26(5)6)58-44(65)36(23-72)57-40(61)29(49)22-71)42(63)55-34(20-38(50)60)47(68)59-15-10-13-37(59)45(66)54-33(18-25(3)4)43(64)56-35(48(69)70)19-27-21-51-30-12-9-8-11-28(27)30/h8-9,11-12,21,24-26,29,31-37,39,51,71-72H,10,13-20,22-23,49H2,1-7H3,(H2,50,60)(H,52,67)(H,53,62)(H,54,66)(H,55,63)(H,56,64)(H,57,61)(H,58,65)(H,69,70)/t29-,31-,32-,33-,34-,35-,36-,37-,39-/m0/s1

InChIKey=GKEWXQLRWDVTMI-KBRUVKHDSA-N


Bioactivity predicted by molecular docking


Database reference: