BIOPEP-UWM: Report

ID 443
Name Dipeptidyl peptidase IV inhibitor
sequence
QPLGYFK
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
7
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 851.9856 Monoisotopic mass 851.4527
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C42H61N9O10/c1-25(2)21-31(50-40(58)34-12-8-20-51(34)41(59)29(44)17-18-35(45)53)37(55)46-24-36(54)47-32(23-27-13-15-28(52)16-14-27)38(56)49-33(22-26-9-4-3-5-10-26)39(57)48-30(42(60)61)11-6-7-19-43/h3-5,9-10,13-16,25,29-34,52H,6-8,11-12,17-24,43-44H2,1-2H3,(H2,45,53)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,60,61)/t29-,30-,31-,32-,33-,34-/m0/s1

InChIKey=KZLAMKUKFAAFDM-CVUOCSEZSA-N


Bioactivity predicted by molecular docking


Database reference: