BIOPEP-UWM: Report

ID 444
Name Dipeptidyl peptidase IV inhibitor
sequence
FMLM
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
4
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 540.7395 Monoisotopic mass 540.2431
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C25H40N4O5S2/c1-16(2)14-21(24(32)28-20(25(33)34)11-13-36-4)29-23(31)19(10-12-35-3)27-22(30)18(26)15-17-8-6-5-7-9-17/h5-9,16,18-21H,10-15,26H2,1-4H3,(H,27,30)(H,28,32)(H,29,31)(H,33,34)/t18-,19-,20-,21-/m0/s1

InChIKey=YRJVDHWOEBVCMC-TUFLPTIASA-N


Bioactivity predicted by molecular docking

Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH) according to the BIOPEP-UWM Virtual database (ID 378)


Database reference: