BIOPEP-UWM: Report

ID 449
Name Dipeptidyl peptidase IV inhibitor
sequence
APLY
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
4
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 462.5379 Monoisotopic mass 462.2470
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C23H34N4O6/c1-13(2)11-17(25-21(30)19-5-4-10-27(19)22(31)14(3)24)20(29)26-18(23(32)33)12-15-6-8-16(28)9-7-15/h6-9,13-14,17-19,28H,4-5,10-12,24H2,1-3H3,(H,25,30)(H,26,29)(H,32,33)/t14-,17-,18-,19-/m0/s1

InChIKey=DLHRNUAODHRKSG-QZHFEQFPSA-N


Bioactivity predicted by molecular docking

Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH) according to the BIOPEP-UWM Virtual database (ID 380)


Database reference:
BIOPEP-UWM Virtual database: ID 380