BIOPEP-UWM: Report

ID 451
Name Dipeptidyl peptidase IV inhibitor
sequence
MMPY
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
4
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 540.6966 Monoisotopic mass 540.2068
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCSC)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C24H36N4O6S2/c1-35-12-9-17(25)21(30)26-18(10-13-36-2)23(32)28-11-3-4-20(28)22(31)27-19(24(33)34)14-15-5-7-16(29)8-6-15/h5-8,17-20,29H,3-4,9-14,25H2,1-2H3,(H,26,30)(H,27,31)(H,33,34)/t17-,18-,19-,20-/m0/s1

InChIKey=CJNANIUWLKGAHG-MUGJNUQGSA-N


Bioactivity predicted by molecular docking

Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH) according to the BIOPEP-UWM Virtual database (ID 381)


Database reference:
BIOPEP-UWM Virtual database: ID 381