BIOPEP-UWM: Report

ID 452
Name Dipeptidyl peptidase IV inhibitor
sequence
CQGR
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
4
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 462.5243 Monoisotopic mass 462.2003
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCSC)C(=O)O

InChI=1S/C31H54N6O11S/c1-15(2)14-21(35-30(46)24(16(3)4)36-26(42)18(32)8-10-22(38)39)28(44)37-25(17(5)6)29(45)33-19(9-11-23(40)41)27(43)34-20(31(47)48)12-13-49-7/h15-21,24-25H,8-14,32H2,1-7H3,(H,33,45)(H,34,43)(H,35,46)(H,36,42)(H,37,44)(H,38,39)(H,40,41)(H,47,48)/t18-,19-,20-,21-,24-,25-/m0/s1

InChIKey=TZVBOTRIOLUHIZ-FYVXYBBASA-N


Bioactivity predicted by molecular docking

Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH) according to the BIOPEP-UWM Virtual database (ID 382)


Database reference:
BIOPEP-UWM Virtual: ID 382