BIOPEP-UWM: Report

ID 456
Name Dipeptidyl peptidase IV inhibitor
sequence
RPPPPLGF
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
8
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 880.0419 Monoisotopic mass 879.4952
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C43H7N11O9/c1-26(2)23-29(36(56)48-25-35(55)49-30(42(62)63)24-27-11-4-3-5-12-27)50-37(57)31-14-7-19-51(31)39(59)33-16-9-21-53(33)41(61)34-17-10-22-54(34)40(60)32-15-8-20-52(32)38(58)28(44)13-6-18-47-43(45)46/h28-34H/t28-,29-,30-,31-,32-,33-,34-/m0/s1

InChIKey=XJTAKHKORMIQMI-NXBWRCJVSA-N


Bioactivity predicted by molecular docking


Database reference:
BIOPEP-UWM Virtual: ID 383