BIOPEP-UWM: Report

ID 457
Name Dipeptidyl peptidase IV inhibitor
sequence
PMAVY
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
5
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 579.7082 Monoisotopic mass 579.2717
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C27H5N5O7S/c1-15(2)22(26(37)31-21(27(38)39)14-17-7-9-18(33)10-8-17)32-23(34)16(3)29-25(36)20(11-13-40-4)30-24(35)19-6-5-12-28-19/h16,19-22H/t16-,19-,20-,21-,22-/m0/s1

InChIKey=JYUXSYWKHHJBDT-XSXWSVAESA-N


Bioactivity predicted by molecular docking

Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH) according to the BIOPEP-UWM Virtual database (ID 384)


Database reference:
BIOPEP-UWM Virtual: ID 384