BIOPEP-UWM: Report

ID 459
Name Dipeptidyl peptidase IV inhibitor
sequence
PTHLW
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
5
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 652.7394 Monoisotopic mass 652.3323
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C32H44N8O7/c1-17(2)11-24(29(43)39-26(32(46)47)12-19-14-35-22-8-5-4-7-21(19)22)37-30(44)25(13-20-15-33-16-36-20)38-31(45)27(18(3)41)40-28(42)23-9-6-10-34-23/h4-5,7-8,14-18,23-27,34-35,41H,6,9-13H2,1-3H3,(H,33,36)(H,37,44)(H,38,45)(H,39,43)(H,40,42)(H,46,47)/t18-,23+,24+,25+,26+,27+/m1/s1

InChIKey=HOQVGAJORPEYHY-PQJUDCBGSA-N


Bioactivity predicted by molecular docking


Database reference: