BIOPEP-UWM: Report

ID 46
Name Antiviral peptide
sequence
LRP

Function:
Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB ID: 6LU7)
 
Number of residues
3
Activity code
avi
Activity :
antiviral
Chemical mass 384.4725 Monoisotopic mass 384.2478
EC50 :
0.00 µM



Bibliographic data:
Authors
Zhao W., Li W., Yu Z., Wu S., Ding L., Liu J.
Title
Identification of lactoferrin-derived peptides as potential inhibitors against the main protease of SARS-CoV-2. LWT, 154, 112684, 2022
Year Source
2022 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@@H]1C(=O)O

InChI=1S/C17H32N6O4/c1-10(2)9-11(18)14(24)22-12(5-3-7-21-17(19)20)15(25)23-8-4-6-13(23)16(26)27/h10-13H,3-9,18H2,1-2H3,(H,22,24)(H,26,27)(H4,19,20,21)/t11-,12-,13-/m0/s1

InChIKey=IBMVEYRWAWIOTN-AVGNSLFASA-N


Bioactivity predicted using molecular docking


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 3543); the ChEMBL database; the EROP-Moscow database; the MBPDB database





Database reference:
Database reference:
AHTPDB: ID 1168; 1280; 1285; 1635; 1871; 1876; 1932; 1963; 2102; 2565; 2570; 2663; 2732; 2862; 3518; 4801; 5094; 5236; 5608; 5669; 5800; 6280; 6460

BindingDB: ID 50169168

BioPepDB: ID biopep00884

BIOPEP-UWM database of bioactive peptides: ID 3543

BIOPEP-UWM database of sensory peptides and amino acids: ID 437

BRENDA: Ligand Leu-Arg-Pro

ChEMBL: ID CHEMBL188695

ChemSpider: ID 8105603

EROP-Moscow: ID E09040

FeptideDB: ID 3543

J-GLOBAL: ID 200907045119827381

MBPDB: Peptide LRP

Nikkaji: ID J408.834D

PubChem: CID 9929972

SATPdb: ID satpdb28676

ZINC: ID ZINC04899610