BIOPEP-UWM: Report

ID 463
Name Dipeptidyl peptidase IV inhibitor
sequence
FAEAC
Function:
Predicted inhibitor of Dipeptidyl peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) (PDB ID: 4A5S)
 
Number of residues
7
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 539.6016 Monoisotopic mass 539.2042
EC50 :
0.00 µM


Bibliographic data:
Authors
Mudgil P., Gan C.-Y., Yap P.-G., Redha A. A., Reem H., Alsaadi S., Mohteshamuddin K., Aguilar-Toalá J. E., Vidal-Limon A. M., Liceaga A. M., Maqsood S.
Title
Exploring the dipeptidyl peptidase IV inhibitory potential of probiotic-fermented milk: An in vitro and in silico comprehensive investigation into peptides from milk of different farm animals. J. Dairy Sci., 107, 10153-10173, 2024
Year Source
2024 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CS)C(=O)O

InChI=1S/C23H33N5O8S/c1-12(25-21(33)15(24)10-14-6-4-3-5-7-14)19(31)27-16(8-9-18(29)30)22(34)26-13(2)20(32)28-17(11-37)23(35)36/h3-7,12-13,15-17,37H,8-11,24H2,1-2H3,(H,25,33)(H,26,34)(H,27,31)(H,28,32)(H,29,30)(H,35,36)/t12-,13-,15-,16-,17-/m0/s1

InChIKey=VMKOPAYTKZVLLX-PTTAZLHSSA-N


Bioactivity predicted by molecular docking

Predicted inhibitor of pancreatic lipase (EC 3.4.23.1) (PDB ID: 1ETH) according to the BIOPEP-UWM Virtual database (ID 386)


Database reference:
BIOPEP-UWM Virtual database: ID 386