BIOPEP-UWM: Report

ID 473
Name Hyaluronidase inhibitor
sequence
PGPPGR
Function:
Predicted ligand of Hyaluronidase (EC 3.2.1.35) (PDB: ID 2PE4)
 
Number of residues
6
Activity code
hyal
Activity :
Hyaluronidase inhibitor
Chemical mass 579.6475 Monoisotopic mass 579.3120
EC50 :
0.00 µM


Bibliographic data:
Authors
Xue W., Kuang X., Meng X., Sun B., Zhao Z., Liang G.
Title
Identification and inhibition mechanism of novel collagen-derived hyaluronidase inhibitory peptides. Food Biosci., 66, 106263, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM Virtual database


SMILES: N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C25H41N9O7/c26-25(27)29-10-2-6-16(24(40)41)32-19(35)13-30-22(38)17-7-3-12-34(17)23(39)18-8-4-11-33(18)20(36)14-31-21(37)15-5-1-9-28-15/h15-18,28H,1-14H2,(H,30,38)(H,31,37)(H,32,35)(H,40,41)(H4,26,27,29)/t15-,16-,17-,18-/m0/s1

InChIKey=HVKNBIOUWPADOU-XSLAGTTESA-N


Bioactivity predicted by molecular docking


Database reference: