BIOPEP-UWM: Report

ID 5
Name Anticancer peptide
sequence
LPHFNS

Function:
Predicted ligand of Keap1 protein (PDB ID: 2FLU)
 
Number of residues
6
Activity code
ac
Activity :
anticancer
Chemical mass 713.7793 Monoisotopic mass 713.3486
EC50 :
0.00 µM



Bibliographic data:
Authors
Chai T.-T., Koh J.-A., Wong C. C.-C., Sabri M.Z., Wong F.-C.
Title
Computational screening for the anticancer potential of seed-derived antioxidant peptides: a cheminformatic approach. Molecules, 26, 7396, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CO)C(=O)O

InChI=1S/C33H47N9O9/c1-18(2)11-21(34)32(49)42-10-6-9-26(42)31(48)40-23(13-20-15-36-17-37-20)29(46)38-22(12-19-7-4-3-5-8-19)28(45)39-24(14-27(35)44)30(47)41-25(16-43)33(50)51/h3-5,7-8,15,17-18,21-26,43H,6,9-14,16,34H2,1-2H3,(H2,35,44)(H,36,37)(H,38,46)(H,39,45)(H,40,48)(H,41,47)(H,50,51)/t21-,22-,23-,24-,25-,26-/m0/s1

InChIKey=XIPWPLHJIZWRDN-FRSCJGFNSA-N


Bioactivity predicted using molecular docking



Database reference: