BIOPEP-UWM: Report

ID 505
Name ACE inhibitor
sequence
LPVSTPGKF

Function:
Predicted ligand of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) (PDB: ID 1o8a)
 
Number of residues
9
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 945.1101 Monoisotopic mass 944.5314
EC50 :
0.00 µM



Bibliographic data:
Authors
Saetang J., Haewphet T., Nilsuwan K., Benjakul S.
Title
ACE- and DPP-IV-inhibitory peptides from bambara groundnut hydrolysate: elucidation using computational tools and molecular docking. Biology, 14, 511, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C45H72N10O12/c1-25(2)21-29(47)43(64)54-19-12-17-34(54)41(62)52-36(26(3)4)42(63)51-32(24-56)39(60)53-37(27(5)57)44(65)55-20-11-16-33(55)40(61)48-23-35(58)49-30(15-9-10-18-46)38(59)50-31(45(66)67)22-28-13-7-6-8-14-28/h6-8,13-14,25-27,29-34,36-37,56-57H,9-12,15-24,46-47H2,1-5H3,(H,48,61)(H,49,58)(H,50,59)(H,51,63)(H,52,62)(H,53,60)(H,66,67)/t27-,29+,30+,31+,32+,33+,34+,36+,37+/m1/s1

InChIKey=WKABMIPYVAMGKC-QAYJJHOASA-N

Activity predicted using molecular docking



Database reference: