BIOPEP-UWM: Report

ID 513
Name Umami peptide
sequence
VLDAPGHRDF

Function:
Predicted ligand of the umami receptors (models based on sequences Q7RTX1 and Q7RTX0)
 
Number of residues
10
Activity code
um
Activity :
umami
Chemical mass 1126.2190 Monoisotopic mass 1125.5550
EC50 :
0.00 µM



Bibliographic data:
Authors
Feng H., Li W., Chang Y., Hong J., He Y., Wu F., He Z.
Title
A novel and efficient technique for peptides preparation coupled with enzyme membrane reactor from Lentinus edodes tails and identification of umami peptides by virtual screening. LWT, 230, 118255, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES:
N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C50H75N15O15/c1-25(2)17-31(63-47(77)40(51)26(3)4)43(73)62-33(20-38(67)68)42(72)58-27(5)48(78)65-16-10-14-36(65)46(76)56-23-37(66)59-32(19-29-22-54-24-57-29)44(74)60-30(13-9-15-55-50(52)53)41(71)61-34(21-39(69)70)45(75)64-35(49(79)80)18-28-11-7-6-8-12-28/h6-8,11-12,22,24-27,30-36,40H,9-10,13-21,23,51H2,1-5H3,(H,54,57)(H,56,76)(H,58,72)(H,59,66)(H,60,74)(H,61,71)(H,62,73)(H,63,77)(H,64,75)(H,67,68)(H,69,70)(H,79,80)(H4,52,53,55)/t27-,30-,31-,32-,33-,34-,35-,36-,40-/m0/s1

InChIKey=XFPHDCSJDCYNOM-SFEYKEBWSA-N


Activity predicted using molecular docking
Models os structures of umami receptors have been obtained using SwissModel program (https://swissmodel.expasy.org/) using PDB ID: 7M3G as a template.



Database reference: