BIOPEP-UWM: Report

ID 547
Name Microbial collagenase inhibitor
sequence
DGNNGR
Function:
Predicted inhibitor of Microbial collagenase (EC 3.4.24.3) (MEROPS ID: M09.002) (PDB ID: 2Y6I)
 
Number of residues
6
Activity code
mci
Activity :
microbial collagenase inhibitor
Chemical mass 631.5948 Monoisotopic mass 631.2666
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhang R., Li Y., Li Y., Zhang H.
Title
Discovering potential anti‑skin‑aging peptides in collagen: computer‑assisted rapid screening and structure–activity relationships. Collagen and Leather, 7, 30, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(=O)O)C(=O)NCC(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CC(=O)N)C(=O)NCC(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C22H37N11O11/c23-9(4-17(38)39)18(40)29-7-16(37)32-12(6-14(25)35)20(42)33-11(5-13(24)34)19(41)30-8-15(36)31-10(21(43)44)2-1-3-28-22(26)27/h9-12H,1-8,23H2,(H2,24,34)(H2,25,35)(H,29,40)(H,30,41)(H,31,36)(H,32,37)(H,33,42)(H,38,39)(H,43,44)(H4,26,27,28)/t9-,10-,11-,12-/m0/s1

InChIKey=GYCFDNQTSOITAJ-BJDJZHNGSA-N


Activity predicted using molecular docking

Predicted inhibitor of pancreatic elastase (EC 3.4.21.36) (PDB ID: 1BRU) according to the BIOPEP-UWM Virtual database


Database reference: