BIOPEP-UWM: Report

ID 551
Name Microbial collagenase inhibitor
sequence
KGVGGDKGE
Function:
Predicted inhibitor of Microbial collagenase (EC 3.4.24.3) (MEROPS ID: M09.002) (PDB ID: 2Y6I)
 
Number of residues
9
Activity code
mci
Activity :
microbial collagenase inhibitor
Chemical mass 845.8952 Monoisotopic mass 845.4229
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhang R., Li Y., Li Y., Zhang H.
Title
Discovering potential anti‑skin‑aging peptides in collagen: computer‑assisted rapid screening and structure–activity relationships. Collagen and Leather, 7, 30, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C34H59N11O14/c1-18(2)29(45-26(49)17-39-30(54)19(37)7-3-5-11-35)33(57)41-14-23(46)38-15-24(47)43-22(13-28(52)53)32(56)44-20(8-4-6-12-36)31(55)40-16-25(48)42-21(34(58)59)9-10-27(50)51/h18-22,29H,3-17,35-37H2,1-2H3,(H,38,46)(H,39,54)(H,40,55)(H,41,57)(H,42,48)(H,43,47)(H,44,56)(H,45,49)(H,50,51)(H,52,53)(H,58,59)/t19-,20-,21-,22-,29-/m0/s1

InChIKey=FOODCHUCPQYZGN-USKNGURMSA-N


Activity predicted using molecular docking

Predicted inhibitor of pancreatic elastase (EC 3.4.21.36) (PDB ID: 1BRU) according to the BIOPEP-UWM Virtual database


Database reference: