BIOPEP-UWM: Report

ID 552
Name Microbial collagenase inhibitor
sequence
GPSGAKGE
Function:
Predicted inhibitor of Microbial collagenase (EC 3.4.24.3) (MEROPS ID: M09.002) (PDB ID: 2Y6I)
 
Number of residues
8
Activity code
mci
Activity :
microbial collagenase inhibitor
Chemical mass 701.7240 Monoisotopic mass 701.3333
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhang R., Li Y., Li Y., Zhang H.
Title
Discovering potential anti‑skin‑aging peptides in collagen: computer‑assisted rapid screening and structure–activity relationships. Collagen and Leather, 7, 30, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CO)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C28H47N9O12/c1-15(33-20(39)12-32-26(46)18(14-38)36-27(47)19-6-4-10-37(19)22(41)11-30)24(44)35-16(5-2-3-9-29)25(45)31-13-21(40)34-17(28(48)49)7-8-23(42)43/h15-19,38H,2-14,29-30H2,1H3,(H,31,45)(H,32,46)(H,33,39)(H,34,40)(H,35,44)(H,36,47)(H,42,43)(H,48,49)/t15-,16-,17-,18-,19-/m0/s1

InChIKey=DJCUGLODMYDMTA-VMXHOPILSA-N


Activity predicted using molecular docking

Predicted inhibitor of pancreatic elastase (EC 3.4.21.36) (PDB ID: 1BRU) according to the BIOPEP-UWM Virtual database


Database reference: