BIOPEP-UWM: Report

ID 555
Name Microbial collagenase inhibitor
sequence
GDKDE
Function:
Predicted inhibitor of Microbial collagenase (EC 3.4.24.3) (MEROPS ID: M09.002) (PDB ID: 2Y6I)
 
Number of residues
5
Activity code
mci
Activity :
microbial collagenase inhibitor
Chemical mass 562.5263 Monoisotopic mass 562.2226
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhang R., Li Y., Li Y., Zhang H.
Title
Discovering potential anti‑skin‑aging peptides in collagen: computer‑assisted rapid screening and structure–activity relationships. Collagen and Leather, 7, 30, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C21H34N6O12/c22-6-2-1-3-10(25-19(36)12(7-16(31)32)24-14(28)9-23)18(35)27-13(8-17(33)34)20(37)26-11(21(38)39)4-5-15(29)30/h10-13H,1-9,22-23H2,(H,24,28)(H,25,36)(H,26,37)(H,27,35)(H,29,30)(H,31,32)(H,33,34)(H,38,39)/t10-,11-,12-,13-/m0/s1

InChIKey=BWJKOTNUUAOIAU-CYDGBPFRSA-N


Activity predicted using molecular docking

Predicted inhibitor of pancreatic elastase (EC 3.4.21.36) (PDB ID: 1BRU) according to the BIOPEP-UWM Virtual database


Database reference: