BIOPEP-UWM: Report

ID 559
Name Tyrosinase inhibitor
sequence
DGCTTHTGE
Function:
Predicted inhibitor of Tyrosinase (EC 1.14.18.1) (PDB ID: 2Y9X)
 
Number of residues
9
Activity code
tyr
Activity :
tyrosinase inhibitor
Chemical mass 919.9121 Monoisotopic mass 919.3329
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhang R., Li Y., Li Y., Zhang H.
Title
Discovering potential anti‑skin‑aging peptides in collagen: computer‑assisted rapid screening and structure–activity relationships. Collagen and Leather, 7, 30, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(C)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C34H53N11O17S/c1-13(46)25(31(58)38-10-21(49)40-18(34(61)62)4-5-23(51)52)43-29(56)19(6-16-8-36-12-39-16)42-32(59)26(14(2)47)45-33(60)27(15(3)48)44-30(57)20(11-63)41-22(50)9-37-28(55)17(35)7-24(53)54/h8,12-15,17-20,25-27,46-48,63H,4-7,9-11,35H2,1-3H3,(H,36,39)(H,37,55)(H,38,58)(H,40,49)(H,41,50)(H,42,59)(H,43,56)(H,44,57)(H,45,60)(H,51,52)(H,53,54)(H,61,62)/t13-,14-,15-,17+,18+,19+,20+,25+,26+,27+/m1/s1

InChIKey=VEKUPGDYQLHHQM-WIQCTOSPSA-N


Activity predicted using molecular docking

Predicted inhibitor of pancreatic elastase (EC 3.4.21.36) (PDB ID: 1BRU) according to the BIOPEP-UWM Virtual database
Predicted inhibitor of Microbial collagenase (EC 3.4.24.3) (MEROPS ID: M09.002) (PDB ID: 2Y6I) according to the BIOPEP-UWM Virtual database


Database reference: