BIOPEP-UWM: Report

ID 565
Name Tyrosinase inhibitor
sequence
AGATGAAGAR
Function:
Predicted inhibitor of Tyrosinase (EC 1.14.18.1) (PDB ID: 2Y9X)
 
Number of residues
10
Activity code
tyr
Activity :
tyrosinase inhibitor
Chemical mass 801.8461 Monoisotopic mass 801.4081
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhang R., Li Y., Li Y., Zhang H.
Title
Discovering potential anti‑skin‑aging peptides in collagen: computer‑assisted rapid screening and structure–activity relationships. Collagen and Leather, 7, 30, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C31H55N13O12/c1-13(32)24(49)36-10-20(46)41-17(5)28(53)44-23(18(6)45)29(54)38-12-22(48)39-15(3)26(51)42-14(2)25(50)37-11-21(47)40-16(4)27(52)43-19(30(55)56)8-7-9-35-31(33)34/h13-19,23,45H,7-12,32H2,1-6H3,(H,36,49)(H,37,50)(H,38,54)(H,39,48)(H,40,47)(H,41,46)(H,42,51)(H,43,52)(H,44,53)(H,55,56)(H4,33,34,35)/t13-,14-,15-,16-,17-,18+,19-,23-/m0/s1

InChIKey=ACLIQRORKVGIMM-RXWFVPBBSA-N


Activity predicted using molecular docking

Predicted inhibitor of pancreatic elastase (EC 3.4.21.36) (PDB ID: 1BRU) according to the BIOPEP-UWM Virtual database
Predicted inhibitor of Microbial collagenase (EC 3.4.24.3) (MEROPS ID: M09.002) (PDB ID: 2Y6I) according to the BIOPEP-UWM Virtual database


Database reference: