BIOPEP-UWM: Report

ID 568
Name Tyrosinase inhibitor
sequence
GMKGHR
Function:
Predicted inhibitor of Tyrosinase (EC 1.14.18.1) (PDB ID: 2Y9X)
 
Number of residues
6
Activity code
tyr
Activity :
tyrosinase inhibitor
Chemical mass 684.8104 Monoisotopic mass 684.3480
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhang R., Li Y., Li Y., Zhang H.
Title
Discovering potential anti‑skin‑aging peptides in collagen: computer‑assisted rapid screening and structure–activity relationships. Collagen and Leather, 7, 30, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCCCN)C(=O)NCC(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C27H48N12O7S/c1-47-10-7-18(36-21(40)12-29)24(43)38-17(5-2-3-8-28)23(42)34-14-22(41)37-20(11-16-13-32-15-35-16)25(44)39-19(26(45)46)6-4-9-33-27(30)31/h13,15,17-20H,2-12,14,28-29H2,1H3,(H,32,35)(H,34,42)(H,36,40)(H,37,41)(H,38,43)(H,39,44)(H,45,46)(H4,30,31,33)/t17-,18-,19-,20-/m0/s1

InChIKey=BMNWITNYIOILCA-MUGJNUQGSA-N


Activity predicted using molecular docking

Predicted inhibitor of pancreatic elastase (EC 3.4.21.36) (PDB ID: 1BRU) according to the BIOPEP-UWM Virtual database
Predicted inhibitor of Microbial collagenase (EC 3.4.24.3) (MEROPS ID: M09.002) (PDB ID: 2Y6I) according to the BIOPEP-UWM Virtual database


Database reference: