BIOPEP-UWM: Report

ID 57
Name Antiviral peptide
sequence
LLY

Function:
Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB ID: 6LU7)
 
Number of residues
3
Activity code
avi
Activity :
antiviral
Chemical mass 407.5025 Monoisotopic mass 407.2412
EC50 :
0.00 µM



Bibliographic data:
Authors
Behzadipour Y., Gholampour M., Pirhadi S., Seradj H., Khoshneviszadeh M., Hemmati S.
Title
Viral 3CLpro as a target for antiviral intervention using milk‑derived bioactive peptides. Int. J. Pept. Res. Therapeut., 27, 2703–2716, 2021
Year Source
2021 Journal



Additional information:
BIOPEP-UWM Virtual database


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C21H33N3O5/c1-12(2)9-16(22)19(26)23-17(10-13(3)4)20(27)24-18(21(28)29)11-14-5-7-15(25)8-6-14/h5-8,12-13,16-18,25H,9-11,22H2,1-4H3,(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1

InChIKey=UCNNZELZXFXXJQ-BZSNNMDCSA-N

Bioactivity predicted using molecular docking


Immunomodulatory pepeptide according to the BIOPEP-UWM database of bioactive peptides (ID 3065), the EROP-Moscow database; the MBPDB database
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 10167); the MBPDB database
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 101168); the MBPDB database



Database reference:
ACToR: ID 20368-24-5

BIOPEP-UWM database of bioactive peptides: ID 3065; 10167; 10168

BRENDA: Ligand Leu-Leu-Tyr

ChEBI: ID 6415

ChemIDplus: ID 20368-24-5

ChemSpider: ID 79864

CTD: ID 20368-24-5

EROP-Moscow: ID E01884

FeptideDB: ID 3065

J-GLOBAL: ID 200907096522740788

KEGG: ID C11331

MBPDB: Peptide LLY

Nikkaji: ID J492.339A

PubChem: CID 88513